Publications

Scientific

Published Works

Modulation of the Extracellular Matrix by Trace Elements, Selenium, Zinc and Manganese in Different Pathologies: An Overview

An adequate tissue level of Trace Elements (TE) is associated with good human health, and the excess or deficiency of TE has been correlated with the appearance of different diseases, including autoimmune, metabolic, neurodegenerative, muscular, cancer, among others.

Effects of Oligoelements Se, Zn, and Mn plus Lachesis Muta Venom in Experimental Scleroderma

Esclerodermia Experimental. Biological Trace Element Research 2013.

Radioprotection of Sensitive Rat Tissues by Oligoelements Se, Zn, Mn Plus Lachesis Muta Venom

J-STAGE, Japan Science and Technology Information Aggregator, Electronic Journal of Radiation Research (Tokyo). 2011 ; 52(5):557-67.

Radioprotective potential of a novel therapeutic formulation of oligoelements Se, Zn, Mn plus Lachesis muta venom.

J Radiat Res (Tokyo). 2009 Nov;50(6):537-44. Epub 2009 Oct 12.

Venomics of the Central and South American Bushmaster snake: comparison of Lachesis muta toxin composition through proteomic and transcriptomic analysis

Journal of Proteomics. 2007 Epub, 2008 30;71(1):46-60, pISSN 1874-3919.

Role of histamine in human breast carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment

Cancer Biology and Therapy 2008; 7(1): 28-35.

Effect of rosiglitazone on N-nitroso-N-methylurea–induced mammary tumors in rats

Full paper edited and distributed on CD-ROM, pp. 1–6, TS I.2.2 ID 2775. Special edition of the 12th International Congress of IRPA – International Radiation Protection Association. 2008. Buenos Aires, Argentina.

Mechanisms underlying the radioprotective effect of histamine on small intestine.

International Journal of Radiation Biology 83(10):653-63, 2007.

Effect of rosiglitazone on N-nitroso-N-methylurea induced mammary tumors in rat.

Anticancer Research 26:2113-2122, 2006.

Modulation of the Extracellular Matrix by Trace Elements, Selenium, Zinc and Manganese in Different Pathologies: An Overview

An adequate tissue level of Trace Elements (TE) is associated with good human health, and the excess or deficiency of TE has been correlated with the appearance of different diseases, including autoimmune, metabolic, neurodegenerative, muscular, cancer, among others.

Effects of Oligoelements Se, Zn, and Mn plus Lachesis Muta Venom in Experimental Scleroderma

Esclerodermia Experimental. Biological Trace Element Research 2013.

Modulation of antioxidant enzymes as a radioprotective mechanism of trace elements and Lachesis muta venom in healthy tissues

Full paper edited on magnetic media. VII Regional Congress of Radiation Protection and I Regional Congress of the International Radiation Protection Association (IRPA), 2006.
Download file

Resistance to ionizing radiation in human melanoma cells: role of antioxidant enzymes and reactive oxygen species

Full paper edited on magnetic media. VII Regional Congress of Radiation Protection and I Regional Congress of IRPA, 2006.

Mechanisms involved in the radioprotective effect of insulin-like growth factor 1 (IGF-I) on the small-intestine mucosa

Full paper edited on magnetic media. VII Regional Congress of Radiation Protection and I Regional Congress of IRPA, 2006.

Histamine inhibits cell proliferation and modulates the expression of Bcl-2 family proteins via the H2 receptor in human pancreatic cancer cells.

Anticancer Res. 2006 Nov-Dec;26(6B):4443-50.

Effect of glibenclamide on N-nitroso-N-methylurea-induced mammary tumors in diabetic and nondiabetic rats.

Oncol Res. 2005;15(6):301-11.

Trace elements Se, Zn, Mn with Lachesis muta as radioprotectors of normal tissues and radiosensitizers of malignant cells

Abstract and full paper. Special IRPA edition, edited and distributed on magnetic media. ID code: 825, 2004.

Radiosensitivity of human melanoma cell lines.

Abstract and full paper. Special IRPA edition, distributed on CD. ID code: 836, 2004.

Greater tolerance to high cytostatic doses with trace elements Mn, Se, and Zn combined with Lachesis muta venom: in vivo and in vitro studies

Journal of Trace Elements in Experimental Medicine. 2003; 16:39–53.

Effect of trace elements and phospholipases in the treatment of experimental breast carcinomas

Prensa Médica Argentina 80:140-144, 1993.

Comparative study of intramuscular Meptazinol and Dipyrone to evaluate analgesic effects in patients undergoing cesarean section

La Semana Médica, Nº 5370, 168:21-25, 1986.

Phospholipase A2 and trace elements Zn, Se, and Mn in the treatment of breast cancer: 1,086 cases, 7-year follow-up

Abstract and full paper. 17th International Cancer Congress, International Proceedings Division, Rio de Janeiro, Brazil: 849–854, 1998 (ISBN 88-323-0824-x). Abstract 283.

Increased tolerance to high doses of ionizing radiation and chemotherapy thanks to trace elements and phospholipase A2

Abstract and full paper. 17th International Cancer Congress, International Proceedings Division, Rio de Janeiro, Brazil: 1495–1499, 1998 (ISBN 88-323-0824-x). Abstract 236.

Published Abstracts

Effect of trace elements and Lachesis muta venom on chemical colon carcinogenesis in rats

E.J.V. Crescenti, L. Sambuco, M. Croci, E. Rivera, V. Medina, R. Nuñez, R. Bergoc
Biocell 34 (Suppl):66, CB-P16, 2010. (ISSN 0327-9545). Edited by IHEM, UNCuyo

The histamine H4 receptor ligand JNJ7777120 inhibits lung metastases in mice bearing MDA-MB-231 xenograft tumors

V. Medina, M. Croci, G. Cricco, E. Crescenti, R. Bergoc, E. Rivera
Programme and Abstracts of the European Histamine Research Society, XXXVIII Annual Meeting, P28, p. 90, 2009

Histamine protects bone marrow from ionizing radiation–induced cellular damage

V. Medina, M. Croci, E. Crescenti, L. Sambuco, N. Massari, G. Cricco, G. Martín, R. Bergoc, E.S. Rivera
Abstract Book, ID: 2775, 12th International Congress of Radiation Protection – IRPA, 2008

Harmful effect of ionizing radiation on immunity; protective effect of a new therapeutic formulation composed of Zn, Se, and Mn plus Lachesis muta venom (O-LM)

E.J. Crescenti, G. Cremaschi, A. Genaro, M. Croci, L. Sambuco, G. Cricco, G. Martín, R. Bergoc, E. Rivera
Abstract Book, ID: 2776, 12th International Congress of Radiation Protection – IRPA, 2008

Gene expression profiles involved in survival and progression mechanisms modulated by trace elements and Lachesis muta venom in MDA-MB-231 breast cancer cells using macroarray analysis

E. J. Crescenti, V. Medina, M. Croci, R. Bergoc, F. Sanchez-Jimenez, E. S. Rivera.
Journal of Clinical Oncology (eISSN: 1527-7755, pISSN 0732-183X):26, (May 20 Supplement), abstract 22192, 2008.

Subcellular Localization of Histamine H3 Receptor in Human Mammary Cells.

V. Medina, . Croci, N. Mohamad, E. Crescenti, R. Bergoc, E. Rivera.
Programme and Abstracts del European Histamine Research Society, XXXVII Annual Meeting, O24, pg 51, 2008.

Role of histamine in the regulation of breast carcinogenesis

V. Medina, N. Massari, M. Núñez, G. Cricco, G. Martín, N. Mohamad, E.J.V. Crescenti, R. Bergoc, E. Rivera
Medicina 67 (Suppl. III):78, 2007 (ISSN 0025-7680)

Crucial role of histamine in regulating breast carcinogenesis

V. Medina, E. Melgarejo, E.J.V. Crescenti, N. Massari, M. Núñez, G. Cricco, G. Martín, R. Bergoc, F. Sanchez-Jimenez, E. Rivera
European Histamine Research Society – Abstract Book, O35, p. 62, 2007

Action of a new therapeutic formulation: Zn, Se, and Mn plus Lachesis muta (O-LM) on the harmful immune effects of radiation

E. Rivera, G. Cremaschi, A. M. Genaro, M. Croci, L. Sambuco, G. Cricco, G. Martin, R. Bergoc, E. Crescenti
Journal of Clinical Oncology, 2007 ASCO Annual Meeting Proceedings Part I. Vol 25, No. 18S (June 20 Supplement), 2007: 14116

Mechanisms responsible for the radioprotective effect of histamine in the mouse small intestine

V. Medina, M. Croci, N. Mohamad, N. Massari, G. Cricco, M. Núñez, G. Martín, A. Gutiérrez, S. Lorena, E.J.V. Crescenti, R. Bergoc, E. Rivera.
Medicina 66(Supl II): 200-201, 2006. (ISSN 0025-7680).

Expression of histamine H3 and H4 receptors in benign lesions and carcinomas of the human mammary gland

V. Medina, M. Croci, E.J.V. Crescenti, N. Mohamad, N. Massari, G. Cricco, M. Núñez, G. Martín, R. Bergoc, E. Rivera.
Medicina 66(Supl II): 198, 2006. (ISSN 0025-7680).

Mechanisms involved in the radioprotective effect of insulin-like growth factor-1 (IGF-1) on the small-intestine mucosa

N. Mohamad, V. Medina, L. Sambuco, A. Gutiérrez, M. Núñez, G. Martín, G. Cricco, E. Rivera, M. Croci, E. Crescenti, R. Bergoc
Abstracts of the VII Regional Congress of Radiation Protection and I Regional Congress of the International Radiation Protection Association (IRPA), 2006

Resistance to ionizing radiation in human melanoma cells: role of antioxidant enzymes and reactive oxygen species

V. Medina, G. Cricco, N. Massari, M. Núñez, G. Martín, N. Mohamad, A. Gutiérrez, E.J.V. Crescenti, M. Croci, R. Bergoc, E. Rivera
Abstracts of the VII Regional Congress of Radiation Protection and I Regional Congress of IRPA, 2006

Modulation of antioxidant enzymes as a radioprotective mechanism of trace elements and Lachesis muta venom in healthy tissues

E.J.V. Crescenti, N. Mohamad, V. Medina, L. Sambuco, A. Gutiérrez, M. Croci, M. Núñez, G. Martín, G. Cricco, R. Bergoc, E. Rivera
Abstracts of the VII Regional Congress of Radiation Protection and I Regional Congress of IRPA, 2006

Immunological mechanisms involved in the antitumor effect produced by trace elements Zn, Se, and Mn plus Lachesis muta venom (O-LM)

E.J.V. Crescenti, M. Croci, G. Cremaschi, A. Genaro, G. Cricco, G. Martín, L. Sambuco, R. Bergoc, E. Rivera
Abstract Book of the 19th Meeting of the European Association for Cancer Research (EACR), Budapest, Hungary, 2006

Molecular and immunological basis of a new therapeutic formulation: trace elements Zn, Se, and Mn plus Lachesis muta venom (O-LM)

E.J.V. Crescenti, M. Croci, G. Cremaschi, A. Genaro, N. Mohamad, L. Sambuco, V. Medina, R. Bergoc, E. Rivera
Journal of Clinical Oncology (ASCO Proceedings). Abstract number: 06-AB-31506-ASCO, 2006

Combined in vivo treatment of pancreatic cancer with trace elements Se, Zn, Mn plus Lachesis muta and gemcitabine

N. Mohamad, E.J.V. Crescenti, M. Croci, G. Martín, G. Cricco, G. Gutiérrez, V. Medina, G. Garbarino, E. Rivera, R. Bergoc
Biocell 29 (Suppl):102, CB-P24, 2005 (ISSN 0327-9545). Published by IHEM, UNCuyo

Antineoplastic effect of hypoglycemic drugs on experimental mammary tumors and malignant cell lines

M. Núñez, C. Cocca, A. Gutiérrez, M. Croci, E.J.V. Crescenti, G. Martín, G. Cricco, E. Rivera, R. Bergoc
Anticancer Research 24(5D):43, 3435, 2004 (ISSN 0250-7005). Editor: Athenes J.G. Delinassios

Radiosensitivity of pancreatic carcinoma cells: in vitro and in vivo studies

N. Mohamad, V. Medina, M. Núñez, M. Croci, E.J.V. Crescenti, C. Cocca, G. Martín, G. Cricco, E. Rivera, R. Bergoc
Anticancer Research 24(5D):39, 3433, 2004 (ISSN 0250-7005). Editor: Athenes J.G. Delinassios

Histamine modulates antioxidant enzyme activity and ROS production in human malignant cell lines

V. Medina, G. Cricco, G. Garbarino, M. Núñez, G. Martín, E.J.V. Crescenti, R. Bergoc, E. Rivera.
Anticancer Research 24(5D): 40, 3433-34, 2004. (ISSN 0250:7005). Editorial: Athenes J.G. Delinassios.

Antitumor action of rosiglitazone: in vivo and in vitro studies

M. Núñez, G. Martín, C. Cocca, C. Kirchheimer, M. Croci, E.J.V. Crescenti, G. Cricco, N. Mohamad, V. Medina, E. Rivera, R. Bergoc
Anticancer Research 24(5D):41, 3434, 2004 (ISSN 0250-7005). Editor: Athenes J.G. Delinassios

Molecular mechanism underlying the inhibitory effect on tumor growth produced by the combination of Zn, Se, and Mn with Lachesis muta

E.J.V. Crescenti, R. Bergoc, M. Croci, V. Medina, G. Cricco, G. Martín, G. Garbarino, M. Núñez, E. Rivera
Anticancer Research 24(5D):42, 3434–35, 2004 (ISSN 0250-7005). Editor: Athenes J.G. Delinassios

Molecular mechanisms involved in the antitumor effect of trace elements Se, Zn, and Mn plus Lachesis muta – in vitro and in vivo studies

E.J.V. Crescenti, M. Croci, E. Rivera, G. Cricco, G. Martín, V. Medina, M. Núñez, N. Mohamad, L. Sambucco, R. Bergoc
Proceedings of the 18th Meeting of the European Association for Cancer Research, Innsbruck, Austria, p. 168, 2004

Protective effect of trace elements and Lachesis muta against high doses of ionizing radiation in normal tissues – in vitro and in vivo studies

E. J.V. Crescenti, M. Croci, E. Rivera, G. Cricco, G. Martín, V. Medina, M. Núñez, N. Mohamad, L. Sambuco, R. Bergoc.
Proceeding of the 18th Meeting of the European Association for Cancer Research, Innsbruck, Austria, pg. 118, 2004.

Radiosensitivity of human melanoma cell lines.

R. Bergoc, V. Medina, G. Cricco, N. Mohamad, G. Martín, M. Núñez, M. Croci, E.J.V. Crescenti, E. Rivera
Abstract and full paper. Special edition of the International Radiation Protection Association (IRPA), edited and distributed on CD. Abstract code 1a7, 2004

Trace elements Se, Zn, Mn plus Lachesis muta as radioprotectors of normal tissues and radiosensitizers of malignant cells

E.J.V. Crescenti, E. Rivera, M. Croci, V. Medina, G. Cricco, N. Mohamad, G. Martín, M. Núñez, R. Bergoc
Abstract and full paper. Special edition of the International Radiation Protection Association (IRPA), distributed on magnetic media. Full paper ID: 825; abstract code 1a5

Effect of trace elements and Lachesis muta venom on breast tumor cells – in vitro and in vivo study

Ernesto J.V. Crescenti, Máximo Croci, Graciela Cricco, Gabriela Martín, Vanina Medina, Mariel Núñez, Nora Mohamad, Rosa Bergoc, Elena Rivera
Abstract published on CD-ROM at the IV Mastology Congress of MERCOSUR, 2003, Buenos Aires, Argentina

Effect of trace elements Se, Zn, and Mn plus Lachesis muta on the growth of the PANC-1 cell line – in vitro and in vivo studies

E.J.V. Crescenti, E. Rivera, M. Croci, G.M. Cricco, G.A. Martín, R.M. Bergoc
International Journal of Cancer S13:193, 2002 (ISSN 0020-7193)

New treatment for advanced pancreatic cancer: 73 patients, 10-year follow-up

 E.J.V. Crescenti, E.J. Alegre, M. Croci
International Journal of Cancer S13:245, 2002 (ISSN 0020-7193)

Greater tolerance to high doses of ionizing radiation and chemotherapy with trace elements plus phospholipase A2

E.J.V. Crescenti, M. Croci, E. Rivera, R. Bergoc
Proceedings of the 17th International Cancer Congress, Bologna, Italy 2:1495–1499, 1998

A2 phospholipase and oligoelements Zn, Se and Mn in breast cancer treatment; 1086 cases, 7 years follow-up.

E. Crescenti, M. Croci, G. Pereyra, J. Cantarella
Abstract and full paper. 17th International Cancer Congress, Rio de Janeiro, Brazil: 849–854, 1998 (ISBN 88-323-0824-x). Abstract 283

Increased tolerance to high doses of ionizing radiation and chemotherapy with trace elements plus phospholipase A2

 E.J.V. Crescenti, M. Croci, E. Rivera, R. Bergoc
Abstract and full paper. 17th International Cancer Congress, Rio de Janeiro, Brazil: 1495–1499, 1998 (ISBN 88-323-0824-x). Abstract 236

Effect of trace elements and phospholipase A2 on tumor cell growth and induction of apoptosis – in vitro studies

E.J.V. Crescenti, M. Croci, R. Bergoc, A. Crescenti, E. Rivera
Abstracts of the First International Meeting on Advances of Cancer Management, UICC, Vienna, Austria 1(247):68, 1997

Effect of trace elements and phospholipase A2 on tumor cell growth – in vivo studies

E.J.V. Crescenti, M. Croci, E. Rivera, A. Crescenti, R. Bergoc
Abstracts of the First International Meeting on Advances of Cancer Management, UICC, Vienna, Austria 1(248):68, 1997

Action of trace elements and phospholipase A2 in increasing tolerance to treatment with high cytostatic doses

 E.J.V. Crescenti, M. Croci, E. Rivera, A. Crescenti, R. Bergoc
Abstracts of the First International Meeting on Advances of Cancer Management, UICC, Vienna, Austria 1(161):45, 1997

Effect of trace elements and phospholipases in the treatment of experimental breast carcinomas

E.J.V. Crescenti, M. Croci, R. Bergoc, E. Rivera, A. Camagni
Tumor V6, No. 4, p. 145, 1993

Organochlorine pesticide residues in human breast milk

E. Astolfi, P. Guglielmoni, E.J.V. Crescenti, J. Landoni, C. Gotelli
Boletín de Plaguicidas 23:1–5, 1982

Biliary peritonitis: our experience and statistical considerations in chest trauma

A. Ferrari, O. Ferrari, R. Risignani, E.J.V. Crescenti, E. Abatángelo
Abstract Book of the IV Days of Emergency Pathology, December 1982

Krukenberg tumor: a case report

 I. Carnavesi, O. Rolón, E.J.V. Crescenti, G. Lovazano
Abstract Book of the XVI Argentine Congress of Obstetrics and Gynecology, September 1979

Breast carcinoma in pregnancy and lactation and mammary lymphosarcoma: therapeutic approach at stage IV

O. Rolón, E.J.V. Crescenti
Abstract Book of the VI Argentine Days of Mastology, October 1979